Automating Drug Discovery

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Computational models have become essential tools for understanding signalling networks and their non-linear dynamics. However, these models are typically constructed manually using prior knowledge and can be over-reliant on study bias. Scaling up the construction and analysisof models to take advantage of increasingly abundant ‘omics data can bridge these gaps by providing a comprehensive view of signalling events and how they influence cellular phenotypes.

Image credit: Adapted from Clarke, Barker & Sun et al. (2025). CC-BY 4.0

Matthew A. Clarke
Matthew A. Clarke
Associate Staff Visitor

Associate Staff Visitor at UCL and Research Fellow at SPAR (https://sparai.org/) working on mechanistic interpratibility.