Publications

Localized immune surveillance of primary melanoma in the skin deciphered through executable modeling
Rowan Howell, James Davies, Matthew A. Clarke, Anna Appios, Inês Mesquita, Yashoda Jayal, Ben Ringham-Terry, Isabel Boned Del Rio, Jasmin Fisher, Clare L. Bennett
PDF Dataset Project DOI
HOXA9 has the hallmarks of a biological switch with implications in blood cancers
Laure Talarmain, Matthew A. Clarke, David Shorthouse, Lilia Cabrera-Cosme, David G. Kent, Jasmin Fisher, Benjamin A. Hall
PDF Code Dataset Project DOI
Executable Network of SARS-CoV-2-Host Interaction Predicts Drug Combination Treatments
Rowan Howell, Matthew A. Clarke, Ann-Kathrin Reuschl, Tianyi Chen, Sean Abbott-Imboden, Mervyn Singer, David M. Lowe, Clare L. Bennett, Benjamin Chain, Clare Jolly, Jasmin Fisher
PDF Dataset Project DOI
Executable cancer models: successes and challenges
Matthew A. Clarke, Jasmin Fisher
PDF DOI
Prognostic hallmarks in AML
Matthew A. Clarke, Jasmin Fisher
PDF DOI
Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling
Peter Kreuzaler, Matthew A. Clarke, Elizabeth J. Brown, Catherine H. Wilson, Roderik M. Kortlever, Nir Piterman, Trevor Littlewood, Gerard I. Evan, Jasmin Fisher
PDF Dataset Project DOI
Using State Space Exploration to Determine How Gene Regulatory Networks Constrain Mutation Order in Cancer Evolution
Matthew A. Clarke, Steven Woodhouse, Nir Piterman, Benjamin A. Hall, Jasmin Fisher
PDF Code Dataset Project DOI
Predictive Computational Modelling of the c-myc Gene Regulatory Network for Combinatorial Treatments of Breast Cancer
Matthew A. Clarke
PDF DOI