Matthew A. Clarke
Matthew A. Clarke
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The Effectiveness and Durability of Pretraining Data Filtering in Protein Language Models
Pretraining filtering is one of the most common safeguards for open-weight language models. Here we study its effectiveness, durability …
Aaron Maiwald
,
Roderick McNeill
,
Jaeyoung Lee
,
Matthew A. Clarke
,
Lennart Justen
,
Alejandro Acelas
,
Ivo Andrews
,
Giles Harper-Donnelly
,
Adam Moore
,
Sophie Rose
,
Oliver M. Crook
,
Felix Jackson
PDF
DOI
Selective Generalization: Improving Capabilities While Maintaining Alignment
Training to improve capabilities may cause undesired changes in model behavior. For example, training models on oversight protocols or …
Ariana Azarbal
,
Matthew A. Clarke
,
Jorio Cocolla
,
Cailley Factor
,
Alex Cloud
PDF
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MAGELLAN: Automated Generation of Interpretable Computational Models for Biological Reasoning
Computational models have become essential tools for understanding signalling networks and their non-linear dynamics. However, these …
Matthew A. Clarke
,
Charlie George Barker
,
Yuxin Sun
,
Theodoros I. Roumeliotis
,
Jyoti S. Choudhary
,
Jasmin Fisher
PDF
Code
Project
DOI
Compositionality and Ambiguity: Latent Co-occurrence and Interpretable Subspaces
Sparse AutoEncoder (SAE) latents show promise as a method for extracting interpretable features from large language models (LM), but …
Matthew A. Clarke
,
Hardik Bhatnagar
,
Joseph Bloom
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