Matthew A. Clarke
Matthew A. Clarke
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BioModelAnalyzer
Using State Space Exploration to Determine How Gene Regulatory Networks Constrain Mutation Order in Cancer Evolution
Cancer develops via the progressive accumulation of somatic mutations, which subvert the normal operation of the gene regulatory …
Matthew A. Clarke
,
Steven Woodhouse
,
Nir Piterman
,
Benjamin A. Hall
,
Jasmin Fisher
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Predictive Computational Modelling of the c-myc Gene Regulatory Network for Combinatorial Treatments of Breast Cancer
As cancer tumours develop, competition between cells will favour those with some mutations over others, creating a dynamic …
Matthew A. Clarke
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