Myeloproliferative Neoplasms

Predicting Cancer Evolution
Cancers evolve from normal cells, and continue to evolve to evade treatment. Understanding evolution from tumourigenesis will allow for earlier detection of cancer, while predicting evolution of resistance mechanisms is essential for finding treatments that are effective in the long term.
Matthew A. Clarke
Clarke et al. (2019) Clarke et al. (2019) Talarmain et al. (2022) Talarmain et al. (2022)
Predicting Cancer Evolution
HOXA9 has the hallmarks of a biological switch with implications in blood cancers
Blood malignancies arise from the dysregulation of haematopoiesis. The type of blood cell and the specific order of oncogenic events …
Laure Talarmain, Matthew A. Clarke, David Shorthouse, Lilia Cabrera-Cosme, David G. Kent, Jasmin Fisher, Benjamin A. Hall
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HOXA9 has the hallmarks of a biological switch with implications in blood cancers